Publication: Incentives conditioned on tenofovir levels to support PrEP adherence among young South African women: a randomized trial

The following article was originally published in the Journal of the International AIDS Society on 28 November 2020. DTHF researchers Katherine Gill and Linda-Gail Bekker are co-authors. The full article can be accessed using the link below.

HIV incidence remains high among African adolescent girls and young women (AGYW), who would benefit from pre‐exposure prophylaxis (PrEP). Strategies to increase PrEP adherence and persistence need to be evaluated in African AGY, including incentives conditional on high adherence.

The 3Ps for Prevention Study was a 12‐month prospective cohort of 200 women ages 16 to 25 initiating PrEP in South Africa from 2017 to 2018. Among these adolescent girls and young women, drug levels indicated high PrEP adherence in almost half of the women at Month 3. Over half persisted with the 12‐month PrEP programme although high adherence declined after Month 3.Strategies to support PrEP adherence and persistence and longer‐acting PrEP formulations are needed.

You can read the full journal article in the November 2020 edition of the Journal of the International AIDS Society.