The Joint Desmond Tutu HIV Foundation (DTHF) – Foundation for Professional Development (FPD) Joint Research Site (referred to as the JRS) is located in the Buffalo City Metro Health District in the Eastern Cape Province. The JRS was initiated as a collaborative research site in 2018, although it has been implementing joint research studies since 2017. The institutional capacity for the DTHF-FPD Joint Research Site fully leverages the institutional capacity of both the DTHF and the FDP. These organizations have successfully collaborated with each other for a number of years. The JRS is a one-hour flight from Cape Town, allowing for efficient travel between the sites.